30. Aceperone
Nomenclature
CAS number: 807-31-8
N-[[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-phenyl-4-piperidinyl]methyl]acetamide; N-[[1-[3-(p-fluorobenzoyl)propyl]-4-phenyl-4-piperidyl]methyl]acetamide; 1-(p-fluorophenyl)-4-(4-phenyl-4-acetamidomethylpiperidino)-1-butanone; 1-[γ-(4-fluorobenzoyl)propyl]-4-acetamidomethyl-4-phenylpiperidine; N-[1-[3-(p-fluorobenzoyl)propyl]-4-phenylpiperidin-4-ylmethyl]acetamide; 4′-fluoro-4-(4-acetamidomethyl-4-phenylpiperido)butyrophenone; acetabutone; acetobuton; R-3248. C24H29FN2O2; mol wt 396.50.
C 72.70%, H 7.37%, F 4.79%, N 7.07%, O 8.07%.
Description and references
Prepd by reacting γ-chloro-4-fluorobutyrophenone with 4-acetamidomethyl-4-phenylpiperidine: P. A. J. Janssen, BE 606849 (1961), corresp to US 3083205 (1961, 1963 both to Janssen). Crystal structure: N. Van Opdenbosch et al., Acta Crystallogr. 33B, 171 (1977).
