71. Acetonylacetone

Nomenclature

CAS number: 110-13-4
2,5-Hexanedione; α,β-diacetylethane.
C6H10O2; mol wt 114.14.
C 63.14%, H 8.83%, O 28.03%.

Description and references

Prepn by decarboxylation of diacetosuccinic ester (from sodium acetoacetic ester and iodine): Paal, Ber. 18, 58 (1885); Knorr, Ber. 22, 2100 (1889); by hydrolysis of 2,5-dimethylfuran: Perkins, Toussaint, US 2052652 (1936 to Union Carbide). Toxicity data: H. F. Smyth, C. P. Carpenter, J. Ind. Hyg. Toxicol. 26, 269 (1944).

Chemical structure

Properties

Liquid, gradually turns yellow. d420 0.970. mp 9°. bp 188°, nD20 1.449. Misc with water, alcohol, ether. LD50 orally in rats: 2.7 g/kg (Smyth, Carpenter).

Caution

A mild local irritant. High concns cause narcosis.