Nomenclature
CAS number: 530-75-6
2-(Acetyloxy)benzoic acid 2-carboxyphenyl ester; 2-hydroxybenzoic acid acetate 2-carboxyphenyl ester; salicylacetylsalicylic acid.
C
16H
12O
6; mol wt 300.26.
C 64.00%, H 4.03%, O 31.97%.
Description and references
Analgesic prepd by treating salicylsalicylic acid q.v., with acetic anhydride
or by fractionating an acetylsalicylic acid melt: DE 236196 (1908 to Boehringer).
Properties
Leaflets from dilute acetic acid, mp 159°; also reported as mp 152°, Rudoi, Sov. Med. 1941, no. 12, 26-27. Practically insol in water, benzene. One part dissolves in 3
parts boiling alcohol, in 70 parts boiling ether, in 45 parts boiling
benzene. Sol in alkaline solns, but is saponified by heating in alk
soln. On acidification of the soln salicylic acid is precipitated.