263. Allobarbital
Nomenclature
CAS number: 52-43-7
5,5-Di-2-propen-1-yl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5,5-diallylbarbituric acid; allobarbitone. C10H12N2O3; mol wt 208.21.
C 57.69%, H 5.81%, N 13.45%, O 23.05%.
Description and references
Prepn: US 1042265 (1912). Acute toxicity: F. Sandberg, Acta Physiol. Scand. 24, 7 (1951).
Properties
Crystals, leaflets. Slightly bitter taste, mp 171-173°. One part dissolves in about 300 parts water, 50 parts boiling water, 20 parts cold alcohol, 20 parts ether; very sol in hot alcohol and in acetone; sol in ethyl acetate. Insol in aliphatic hydrocarbons. A satd aq soln is acid to litmus. LD50 i.p. in rats: 127.3 mg/kg (Sandberg).Note
This is a controlled substance (depressant): 21 CFR, 1308.13.Therapeutic Category
Sedative, hypnotic.
Keywords
Sedative/Hypnotic; Barbituric Acid Derivatives