13-00153. A-Denopterin [Archived]

Nomenclature

CAS number: 25663-23-4
N-[4-[[1-(2,4-Diamino-6-pteridinyl)ethyl]methylamino]benzoyl]-l-glutamic acid; 4-amino-N10,9-dimethylpteroylglutamic acid.
C21H24N8O5; mol wt 468.47.
C 53.84%, H 5.16%, N 23.92%, O 17.08%.

Description and references

Prepn: Hultquist et al., J. Am. Chem. Soc. 71, 619 (1949); Hultquist, Smith, GB 667098 (1952 to Am. Cyanamid).

Chemical structure

Derivative

Dihydrate.

Properties

Yellow-orange microcrystals. uv max (0.1N NaOH): 255, 306, 369 nm (ε 25,000, 25,000, 9000); (0.1N HCl): 244, 316 nm (ε 22,000, 14,000).

Status

This monograph has been retired and is no longer subject to revision or update.