Nomenclature
CAS number: 516-58-5
(5α,20
R)-20-Hydroxypregnan-3-one; 20β-hydroxy-5α-pregnan-3-one; 20β-hydroxy-3-oxo-5α-pregnane.
C
21H
34O
2; mol wt 318.49.
C 79.19%, H 10.76%, O 10.05%.
Description and references
Prepn from allopregnane-3β,20β-diol-3-acetate:
Rubin et al., J. Am. Chem. Soc. 73, 2338 (1951); from isofuntumidine: Janot et
al., Bull. Soc. Chim. Fr. 1960, 1669.
Properties
Crystals from heptane, mp 185°. [α]D +20° (c = 1.2 in chloroform).Derivative
Acetate.
C
23H
36O
3; mol wt 360.53.
C 76.62%, H 10.06%, O 13.31%.
Properties
Crystals from ethanol, mp 148°. [α]D +57° (c = 1.9 in chloroform).