291. Allylestrenol

Nomenclature

CAS number: 432-60-0
(17β)-17-(2-Propen-1-yl)estr-4-en-17-ol; 17-allylestr-4-en-17β-ol; 17α-allyl-17-hydroxy-19-nor-4-androstene; 17-hydroxy-17α-allyl-4-estrene; Gestanin (Organon); Gestanon (Organon); Gestanyn (Organon); Orageston (Organon); Turinal (Gedeon Richter).
C21H32O; mol wt 300.48.
C 83.94%, H 10.73%, O 5.32%.

Description and references

Prepn: GB 841411 (1960 to Organon). Determn in pharmaceutical formulations: S. Gorg et al., Analyst 104, 196 (1979). Clinical experience in pregnancy: J. Cortés-Prieto et al., Clin. Ther. 3, 200 (1980).

Chemical structure

Properties

Crystals, mp 79.5-80°. Practically insol in water. Sol in alcohol, ether, acetone, chloroform. Sensitive to oxidizing agents.

Therapeutic Category

Progestogen.

Keywords

Progestogen