448. 2-Amino-2-methyl-1,3-propanediol

Nomenclature

CAS number: 115-69-5
1,1-Di(hydroxymethyl)ethylamine; 1,3-dihydroxy-2-methyl-2-propylamine; AMPD.
C4H11NO2; mol wt 105.14.
C 45.69%, H 10.55%, N 13.32%, O 30.43%.

Description and references

An amino glycol prepd by reduction of the corresponding nitro compd: O. Piloty, O. Ruff, Ber. 30, 2057 (1897); B. M. Vanderbilt, H. B. Hass, Ind. Eng. Chem. 32, 34 (1940); Johnson, Degering, J. Org. Chem. 8, 7 (1943). Review of uses: G. A. Bergy, J. Am. Pharm. Assoc. Pract. Pharm. Ed. 3, 358-364 (1942). Toxicological evaluation and review: Cosmetic, Toiletry and Fragrance Assoc., J. Am. Coll. Toxicol. 9, 203-228 (1990).

Chemical structure

Properties

Crystalline mass, mp 109-111°. bp10 151-152°. 250 grams dissolve in 100 ml water at 20°. Sol in alcohols. pH of 0.1M aq soln 10.8.

Use

In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, so-called sol oils. In hair sprays, wave sets and other noncoloring hair preparations. Absorbent for acidic gases. Biological buffer.