476. Aminorex

Nomenclature

CAS number: 2207-50-3
4,5-Dihydro-5-phenyl-2-oxazolamine; 2-amino-5-phenyl-2-oxazoline; aminoxafen; aminoxaphen; McN-742.
C9H10N2O; mol wt 162.19.
C 66.65%, H 6.21%, N 17.27%, O 9.86%.

Description and references

Prepn: Poos et al., J. Med. Chem. 6, 266 (1963); Poos, US 3161650 (1964 to McNeil).

Chemical structure

Properties

Crystals from benzene, mp 136-138°.

Derivative

Fumarate.

Nomenclature

CAS number: 13425-22-4
Menocil (Cilag-Chemie); Apiquel (McNeil).
C9H10N2O.C4H4O4; mol wt 278.26.
C 56.11%, H 5.07%, N 10.07%, O 28.75%.

Note

This is a controlled substance (stimulant): 21 CFR, 1308.11.

Therapeutic Category

Anorexic.

Keywords

Anorexic