580. Amperozide

Nomenclature

CAS number: 75558-90-6
4-[4,4-Bis(4-fluorophenyl)butyl]-N-ethyl-1-piperazinecarboxamide; FG-5606.
C23H29F2N3O; mol wt 401.49.
C 68.81%, H 7.28%, F 9.46%, N 10.47%, O 3.99%.

Description and references

Serotonin 5-HT2A receptor antagonist. Prepn: A. K. K. Bjrk et al., DE 2941880; eidem, US 4308387 (1980, 1981 both to Ferrosan). LC-MS determn in swine liver: G. Balizs et al., Analyst 119, 2687 (1994). Mechanism of action study: J. T. Haskins et al., Brain Res. Bull. 19, 465 (1987). Anti-aggressive effects in pigs: J. L. Barnett et al., Appl. Anim. Behav. Sci. 50, 121 (1996).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 86725-37-3
Hogpax.
C23H29F2N3O.HCl; mol wt 437.95.
C 63.08%, H 6.90%, F 8.68%, N 9.59%, O 3.65%, Cl 8.10%.

Properties

mp 177-178°.

Therapeutic Category (Veterinary)

Tranquilizer.