810. Arsonoacetic Acid

Nomenclature

CAS number: 107-38-0
2-Arsonoylacetic acid.
C2H5AsO5; mol wt 183.98.
C 13.06%, H 2.74%, As 40.72%, O 43.48%.

Description and references

Prepn from sodium arsenite and sodium chloroacetate: Palmer, J. Am. Chem. Soc. 45, 3023 (1923); Org. Synth. coll. vol. I, 73 (1941).

Chemical structure

Properties

Shiny plates, mp 152°. Very sol in water, alc; sparingly sol in hot glacial acetic acid. Practically insol in petr ether, benzene, acetone, chloroform, ethyl acetate.

Derivative

Barium salt.
C4H4As2Ba3O10; mol wt 773.89.
C 6.21%, H 0.52%, As 19.36%, Ba 53.24%, O 20.67%.

Properties

Feathery needles. Slightly sol in boiling water.

Derivative

Sodium salt monohydrate.

Nomenclature

Disodium arsonoacetate; disodium acetarsenate; acetarsonic acid disodium salt; sodium acetoarsinate; Aricyl (Winthrop).
C2H3AsNa2O5.H2O; mol wt 245.96.
C 9.77%, H 2.05%, As 30.46%, Na 18.69%, O 39.03%.

Properties

Crystals. Freely sol in water.

Therapeutic Category (Veterinary)

Disodium salt has been used to treat anaplasmosis, and as a stimulant in nervous diseases.