Description and references

Animal feed glycopeptide antibiotic complex produced by Streptomyces candidus. Prodn: M. P. Kunstmann, J. N. Porter, US 3338786 (1967 to Am. Cyanamid). Fermentation, isoln, characterization: M. P. Kunstmann et al., Antimicrob. Agents Chemother. 8, 242 (1968). Isoln, purif of major components: W. J. McGahren et al., J. Antibiot. 36, 1671 (1983). HPLC separation of α-, β-avoparcin: F. Sztaricskai et al., ibid. 1691. Chromatographic determn in tissue: M. S. S. Curren, J. W. King, J. Chromatogr. A 954 41 (2002). Structural studies: J. J. Hlavka et al., Tetrahedron Lett. 1974, 175; W. J. McGahren et al., J. Am. Chem. Soc. 101, 2237 (1979). Structure: eidem, ibid. 102, 1671 (1980). Stereochemistry and epimerization: G. A. Ellestad et al., J. Antibiot. 36, 1683 (1983). Relationship between structure, antibacterial activity: S.W. Fesik et al., Mol. Pharmacol. 25, 275 (1984). Antimicrobial spectrum: M. G. Cormican et al., Diagn. Microbiol. Infect. Dis. 29, 241 (1997). Effect on resistance patterns in chickens: J. R. Walton, Zentralbl. Veterinaermed. (B) 25, 290 (1978), C.A. 89, 173507 (1978). Prevention of exptly induced necrotic enteritis in chickens: J. F. Prescott, Avian Dis. 23, 1072 (1979). Effect on feedlot performance: R. J. Johnson et al., J. Anim. Sci. 48, 1338 (1979).

Properties

Derivative

Derivative