1118. Benzphetamine

Nomenclature

CAS number: 156-08-1
(αS)-N,α-Dimethyl-N-(phenylmethyl)benzeneethanamine; N-benzyl-N,α-dimethylphenethylamine; d-N-methyl-N-benzyl-β-phenylisopropylamine.
C17H21N; mol wt 239.36.
C 85.30%, H 8.84%, N 5.85%.

Description and references

Prepd from d-desoxyephedrine: Heinzelman, Aspergren, US 2789138 (1957 to Upjohn).

Chemical structure

Properties

Liquid. bp0.02 127°. nD19 1.5515. Practically insol in water. Sol in methanol, ethanol, ether, chloroform, acetone, benzene.

Derivative

Hydrochloride.

Nomenclature

CAS number: 5411-22-3
Didrex (Pharmacia & Upjohn); Inapetyl (Pharmacia & Upjohn).
C17H21N.HCl; mol wt 275.82.
C 74.03%, H 8.04%, N 5.08%, Cl 12.85%.

Properties

Crystals from ethyl acetate, mp 129-130°. Dextrorotatory. Sol in water, 95% ethanol.

Note

This is a controlled substance (stimulant): 21 CFR, 1308.13.

Therapeutic Category

Anorexic.

Keywords

Anorexic; CNS Stimulant