1183. Betazole

Nomenclature

CAS number: 105-20-4
1H-Pyrazole-3-ethanamine; 3-(2-aminoethyl)pyrazole; 3-(β-aminoethyl)pyrazole; ametazole; gastramine.
C5H9N3; mol wt 111.15.
C 54.03%, H 8.16%, N 37.80%.

Description and references

Prepd by the catalytic reduction of 3-pyrazoleacetaldehyde hydrazone: Jones, Mann, J. Am. Chem. Soc. 75, 4048 (1953); Jones, US 2785177 (1957 to Lilly).

Chemical structure

Properties

Viscous liquid. bp0.5 118-123°.

Derivative

Dihydrochloride.

Nomenclature

CAS number: 138-92-1
Histimin; Histalog (Lilly).
C5H9N3.2HCl; mol wt 184.07.
C 32.63%, H 6.02%, N 22.83%, Cl 38.52%.

Properties

Crystals from ethanol, mp 224-226°. Sol in water. Practically insol in chloroform. Aq solns are acid to litmus.

Therapeutic Category

Diagnostic aid (gastric secretion stimulant).

Keywords

Diagnostic Aid