1216. Bikhaconitine

Nomenclature

CAS number: 6078-26-8
(1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-8,13,14-triol 8-acetate 14-(3,4-dimethoxybenzoate); acetylveratroylbikhaconine.
C36H51NO11; mol wt 673.79.
C 64.17%, H 7.63%, N 2.08%, O 26.12%.

Description and references

From roots of Aconitum spicatum Stapf., Ranunculaceae: Dunstan, Andrews, J. Chem. Soc. 87, 1636 (1905). Structure: Tsuda, Marion, Can. J. Chem. 41, 3055 (1963).

Chemical structure

Properties

Prisms from n-hexane, mp 163.5-164°.

Derivative

Monohydrate.

Properties

Needles from ether or dil methanol, mp 105-110°. [α]D +16° (c = 1.6 in ethanol). Sol in alcohol, chloroform, ether, dil acids. Practically insol in water, petr ether.