Nomenclature
CAS number: 92-67-1
[1,1′-Biphenyl]-4-amine; 4-aminobiphenyl;
p-aminodiphenyl; anilinobenzene; xenylamine.
C
12H
11N; mol wt 169.22.
C 85.17%, H 6.55%, N 8.28%.
Description and references
Prepn from diazoaminobenzene: Heusler, Ann. 260, 232 (1890). Review
of carcinogenicity studies: IARC Monographs 1, 74-79 (1972).
Properties
Leaflets from alc or water. mp 53°. Volatile with steam. Slightly
sol in cold water, readily sol in hot water, alcohol, chloroform.Caution
Potential symptoms of overexposure
are headache, dizziness; lethargy, dyspnea; ataxia, weakness; methemoglobinemia;
urinary burning; acute hemorrhagic cystitis. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH
97-140, 1997) p 14. This substance is listed as a known human carcinogen:
Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-13.Use
In the detection of sulfates. Formerly as rubber
antioxidant. As carcinogen in cancer research.