1237. Bipiperidyl Mustard
Nomenclature
CAS number: 6802-93-3
1,1′-Bis(2-chloroethyl)-4,4′-bipiperidine; BPM. C14H26Cl2N2; mol wt 293.28.
C 57.33%, H 8.94%, Cl 24.18%, N 9.55%.
Description and references
Obesifying agent causing rapid lipid deposition in mice: Rutman et al., Science 153, 1000 (1966). Activity shown only by the active form, prepd by neutralizing the conjugate acid form and generating a bicyclic ammonium deriv at pH 10. Metabolic studies: eidem, Trans. N.Y. Acad. Sci. 30, 244 (1967). Research use for obesity-producing brain lesions: H.-R. Berthoud, T. L. Powley, Am. J. Physiol. 248, R46 (1985); A. C. Scallet, J. W. Olney, Brain Res. 374, 380 (1986). Toxicity study: E. W. Schafer, Jr. et al., Ecotoxicol. Environ. Saf. 6, 149 (1982).
