1294. Bisoctrizole

Nomenclature

CAS number: 103597-45-1
2,2′-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol]; MBBT; Tinosorb M (Ciba); Tinuvin 360 (Ciba).
C41H50N6O2; mol wt 658.87.
C 74.74%, H 7.65%, N 12.76%, O 4.86%.

Description and references

UV-A filter with dual mechanism of action. Photostable organic molecule with broad UV absorption; microfine structure causes light scattering and reflection. Prepn and use in light stabilizer formulations: N. Kubota, A. Nishimura, EP 180992; eidem, US 4681905 (1986, 1987 both to Adeka Argus). Light stabilization of polymers: G. Rytz et al., Angew. Makromol. Chem. 247, 213 (1997). Skin photoprotection study: C. Gélis et al., Photodermatol. Photoimmunol. Photomed. 19, 242 (2003). HPLC determn in suncare formulations: C. G. Smyrniotakis, H. A. Archontaki, J. Chromatogr. A 1031, 319 (2004). UV attenuating properties of microparticles: B. Herzog et al., J. Colloid Interface Sci. 276, 354 (2004).

Chemical structure

Properties

Slightly yellow powder, mp 195°. Flash pt: >200°C. d20 1.2. Vapor pressure (25°): 6×10-13 Pa. Soly at 20° (%w/w): water < 0.001; acetone 0.05; chloroform 100; n-hexane 0.03; methylene chloride 75; toluene 34. Absorption max (chloroform): 308, 349 nm (ε 31895). Absorption max (n-heptane): 348 nm (ε 31600).

Use

Light stabilizer in polymers and resins.

Therapeutic Category

Ultraviolet screen.

Keywords

Ultraviolet Screen