Nomenclature
CAS number: 122-10-1
3-[(Dimethoxyphosphinyl)oxy]-2-pentenedioic acid 1,5-dimethyl
ester; 3-hydroxyglutaconic acid dimethyl ester dimethyl phosphate; dimethyl 1,3-di(carbomethoxy)-1-propen-2-yl phosphate; dimethyl 3-hydroxyglutaconate dimethyl phosphate; ENT-24833; GC-3707.
C
9H
15O
8P; mol wt 282.18.
C 38.31%, H 5.36%, O 45.36%, P 10.98%.
Description and references
Organophosphate insecticide; cholinesterase
inhibitor. Prepn: Gilbert, US 2891887 (1959 to Allied). Prepn and activity
of isomers: P. E. Newallis et al., J. Agric. Food Chem. 15, 940 (1967) DOI. Mechanism of action: A. Morello et al., Biochem. Pharmacol. 16, 1703 (1967) DOI PubMed.
Properties
Liquid; bp
17 155-164°; bp
2 155-165° (tech grade).
Poisonous. Miscible with methanol, ethanol,
acetone, xylene. Practically insol in water, petr ether, kerosene.
LD
50 in rats, starlings, red-winged
blackbirds (mg/kg): 32, 9.5, 0.95 orally;
see E. W. Schafer,
Toxicol. Appl. Pharmacol. 21, 315 (1972)
DOI PubMed.
Insecticide.