1389. Bromethalin

Nomenclature

CAS number: 63333-35-7
N-Methyl-2,4-dinitro-N-(2,4,6-tribromophenyl)-6-(trifluoromethyl)benzenamine; EL-614; Vengeance (Velsicol).
C14H7Br3F3N3O4; mol wt 577.93.
C 29.10%, H 1.22%, Br 41.48%, F 9.86%, N 7.27%, O 11.07%.

Description and references

Rodenticide which acts by uncoupling oxidative phosphorylation. Single-feed toxicant, effective against warfarin-resistant strains of mice, rats. Prepn and identification as rodenticide: B. A. Dreikorn, US 4187318 (1980 to Eli Lilly). Toxicology and activity: B. A. Dreikorn et al., Proc. Br. Crop Prot. Conf. - Pests Dis. 1979, 491. Review: B. A. Dreikorn, G. O. P. O'Doherty, ACS Symp. Ser. 255, 45-63 (1984).

Chemical structure

Properties

Pale yellow odorless crystals from ethanol, mp 150-151°. Sol in chloroform, acetone; moderately sol in aromatic hydrocarbons. Insol in water. LD50 in mice, rats, cats, dogs (mg/kg): 2, 5, 2, 5 orally (Dreikorn).

Use

Rodenticide.