1411. p-Bromobenzyl Chloroformate

Nomenclature

CAS number: 5798-78-7
Carbonochloridic acid (4-bromophenyl)methyl ester; chloroformic acid p-bromobenzyl ester.
C8H6BrClO2; mol wt 249.49.
C 38.51%, H 2.42%, Br 32.03%, Cl 14.21%, O 12.83%.

Description and references

A stable, low-melting cryst product obtained from p-bromobenzyl alco-hol. In the carbobenzyloxy method of prepn of amino acids and peptides, gives higher melting and better cryst products than the corresp carbobenzyloxy compds: Channing et al., Nature 167, 487 (1951).

Chemical structure

Use

In the prepn of amino acids and peptides.