1419. Bromofenofos

Nomenclature

CAS number: 21466-07-9
3,3′,5,5′-Tetrabromo-[1,1′-biphenyl]-2,2′-diol 2-(dihydrogen phosphate); 3,3′,5,5′-tetrabromo-2,2′-biphenyldiol mono(dihydrogen phosphate); 4,4′,6,6′-tetrabromobiphenyl-2,2′-diol mono(dihydrogen phosphate); bromophenophos; bromphenphos; PH-1882.
C12H7Br4O5P; mol wt 581.77.
C 24.77%, H 1.21%, Br 54.94%, O 13.75%, P 5.32%.

Description and references

Anthelmintic used to control fascioliasis in ruminants. Prepn: NL 6505635; S. Van der Meer et al., US 3662035 (1966, 1972 both to Chemiefarma); S. Van der Meer, H. Pouwels, J. Med. Chem. 12, 534 (1969). Activity: J. Guilhon et al., Bull. Acad. Vet. Fr. 43, 67 (1970). Toxicology: J. M. Poul, M. Dagorn, Recl. Med. Vet. 158, 363 (1982). HPLC determn in plasma: Y. S. Endoh et al., J. Chromatogr. 426, 202 (1988).

Chemical structure

Properties

Cryst, no mp, dec >350°.

Therapeutic Category (Veterinary)

Anthelmintic (Trematodes).