1466. Bucolome

Nomenclature

CAS number: 841-73-6
5-Butyl-1-cyclohexyl-2,4,6(1H,3H,5H)pyrimidinetrione; 5-butyl-1-cyclohexylbarbituric acid; 5-n-butyl-1-cyclohexyl-2,4,6-trioxoperhydropyrimidine; BCP; Paramidin (Takeda).
C14H22N2O3; mol wt 266.34.
C 63.13%, H 8.33%, N 10.52%, O 18.02%.

Description and references

Prepn: Senda et al., US 3243344 and US 3274195 (both 1966 to Takeda). Metabolic studies in man: Yashiki et al., Chem. Pharm. Bull. 19, 468, 869 (1971).

Chemical structure

Properties

Needles from methanol, mp 84°. bp0.8 185-187°.

Therapeutic Category

Anti-inflammatory.

Keywords

Anti-inflammatory (Nonsteroidal)