1543. n-Butylamine

Nomenclature

CAS number: 109-73-9
1-Butanamine; 1-aminobutane.
C4H11N; mol wt 73.14.
C 65.69%, H 15.16%, N 19.15%.

Description and references

Prepn by reduction of butyraldoxime: Lycan et al., Org. Synth. coll. vol. II, 319 (1943). Usually manuf by catalytic alkylation of ammonia with butyl alcohol: Davies et al., US 2609394 (1952 to I.C.I.); Hindley, Fisher, US 2782237 (1957 to British Celanese); Lemon, Myerly, US 3022349 (1962 to Union Carbide); Shirley, Speranza, US 3128311 (1964 to Jefferson Chem.). Manuf from butyraldehyde and ammonia in the presence of Raney nickel: Brimer et al., US 2518659 (1950 to Eastman Kodak). Toxicity study: C. H. Hine et al., Arch. Environ. Health 1, 343 (1960).

Chemical structure

Properties

Liquid, ammoniacal odor, bp 78°. mp -50°. d425 0.7327. nD20 1.4010. Flash pt, open cup: 30°F (-1°C). Flammable, corrosive. Misc with water, alcohol, ether. LD50 orally in rats: 500 mg/kg (Hine).

Caution

Potential symptoms of overexposure are irritation of eyes, skin, nose and throat; headache; skin flushing and burns. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 40.

Use

Intermediate for pharmaceuticals, dyestuffs, rubber chemicals, emulsifying agents, insecticides, synthetic tanning agents.