1559. Butyl Cellosolve(R) (Union Carbide)

Nomenclature

CAS number: 111-76-2
2-Butoxyethanol; ethylene glycol monobutyl ether.
C6H14O2; mol wt 118.17.
C 60.98%, H 11.94%, O 27.08%.

Description and references

Prepn: L. H. Cretcher, W. H. Pittenger, J. Am. Chem. Soc. 46, 1503 (1924); W. W. Carlson, US 2448767 (1948 to Mellon Inst. Ind. Res.); R. Riemschneider, P. Gross, Monatsh. Chem. 90, 783 (1959). Toxicity: H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941); C. P. Carpenter et al., Arch. Ind. Health 14, 114 (1956). Series of articles on toxicology: Environ. Health Perspect. 57, 1-275 (1984). Review of toxicology and human exposure: Toxicological Profile for 2-Butoxyethanol and 2-Butoxyethanol Acetate (PB99-102527, 1998) 404 pp.

Chemical structure

Properties

Liquid, bp 171-172°. d420 0.9012, d2020 0.9019. nD20 1.4196. Flash pt, closed cup: 141°F (60°C). Sol in water, mineral oil, most organic solvents. LD50 orally in rats: 1.48 g/kg (Smyth).

Caution

Potential symptoms of overexposure are hemolysis, hemoglobinuria; CNS depression, headache; vomiting. Direct contact may cause irritation of skin, eyes, nose and throat. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 36. See also Patty's Industrial Hygiene and Toxicology vol. 2D, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 4th ed., 1994) pp 2765, 2795-2804.

Use

Solvent for nitrocellulose, resins, grease, oil, albumin; dry cleaning.