1585. p-tert-Butylphenol
Nomenclature
CAS number: 98-54-4
4-(1,1-Dimethylethyl)phenol; butylphen. C10H14O; mol wt 150.22.
C 79.95%, H 9.39%, O 10.65%.
Description and references
Prepd by heating phenol with isobutanol in the presence of zinc chloride: DE 17311; Frdl. 1, 22; also from phenol, tert-butyl chloride and excess alkali in alcohol: Lewis, J. Chem. Soc. 83, 329 (1903). See also Smith, J. Am. Chem. Soc. 55, 3718 (1933); Natelson, ibid. 56, 1583 (1934); Huston, Hsieh, ibid. 58, 439 (1936); US 2039344 (1936 to Dow); Isagulyants, Bagryantseva, C.A. 33, 8183 (1939). Toxicity study: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1969).
Properties
Needles from water, mp 98°. d4114 0.9081. bp 237°. Volatile with steam. Practically insol in cold water. Sol in alcohol, ether. LD50 orally in rats: 3.25 ml/kg (Smyth).Derivative
Sodium salt.C10H13NaO; mol wt 172.20.
C 69.75%, H 7.61%, Na 13.35%, O 9.29%.