1857. Caroverine

Nomenclature

CAS number: 23465-76-1
1-[2-(Diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]-2(1H)-quinoxalinone; 1-(diethylaminoethyl)-3-(p-methoxybenzyl)dihydro-2-quinoxalone; Spasmium (Donau).
C22H27N3O2; mol wt 365.47.
C 72.30%, H 7.45%, N 11.50%, O 8.76%.

Description and references

Prepn: Zellner et al., US 3028384 (1962 to Donau-Pharm.). Polarographic study: P. Pflegel, Pharmazie 24, 667 (1969). Pharmacological study: F. Hahn et al., Arch. Int. Pharmacodyn. Ther. 199, 108 (1972).

Chemical structure

Properties

Crystals from isopropyl alcohol, mp 69°. bp0.01 202°.

Derivative

Hydrochloride.

Properties

Dec 188°.

Therapeutic Category

Antispasmodic.

Keywords

Antispasmodic