1878. Casanthranol

Nomenclature

Cantralax (Ferrosan); Peristim (Mead Johnson).

Description and references

Complex mixture of the purified anthranol glycosides derived from Cascara sagrada, q.v., practically devoid of free anthraquinones. Two active fractions have been identified as casanthranol A and casanthranol B. Upon oxidative hydrolysis, casanthranol A yields emodin, while casanthranol B under similar treatment yields the aglycone, aloe-emodin, and traces of chrysophanic acid. Prepn: Lee, Berger, US 2552896 (1951 to Hoffmann-La Roche).

Component of Peri-Colace, Casakol.

Therapeutic Category

Cathartic.

Keywords

Laxative/Cathartic