1882. Cascarillin

Nomenclature

CAS number: 10118-56-6
3-(Acetyloxy)-1-[2-(3-furanyl)-2-hydroxyethyl]decahydro-5,6-dihydroxy-2,4a,5-trimethyl-1-naphthalenecarboxaldehyde.
C22H32O7; mol wt 408.49.
C 64.69%, H 7.90%, O 27.42%.

Description and references

From bark of Croton eluteria (L.) Sw., Euphorbiaceae. Isoln: Duval, J. Pharm. 8, 91 (1845); Mylius, Ber. 6, 1051 (1873); Naylor, Littlefield, Pharm. J. 57, 95 (1896). Structure and stereochemistry: McEachan et al., J. Chem. Soc. B 1966, 633.

Chemical structure

Properties

Needles from alc, mp 205°. Very bitter taste. Freely sol in ether, hot alc; slightly sol in water, cold alc, chloroform.

Therapeutic Category

Aromatic bitter.