2116. p-Chloroacetophenone

Nomenclature

CAS number: 99-91-2
1-(4-Chlorophenyl)ethanone; 4′-chloroacetophenone.
C8H7ClO; mol wt 154.59.
C 62.16%, H 4.56%, Cl 22.93%, O 10.35%.

Description and references

Prepd from chlorobenzene and acetic anhydride in the presence of AlCl3: Adams, Noller, Org. Synth. coll. vol. I, 109 (1941). Physical properties: eidem, ibid.; Dreisbach, Martin, Ind. Eng. Chem. 41, 2875 (1949).

Chemical structure

Properties

Liquid, bp24 124-126°, bp 237°. mp 20-21° (Adams, Noller); also reported as 18.4° (Dreisbach, Martin). d420 1.192, d425 1.188. nD20 1.555, nD25 1.553. Practically insol in water. Miscible with alcohol, ether.

Caution

Highly irritating to eyes, mucous membranes.