2207. Choline Dihydrogen Citrate

Nomenclature

CAS number: 77-91-8
(2-Hydroxyethyl)trimethylammonium citrate; Chothyn (Tilden-Yates); Cirrocolina; Citracholine.
C11H21NO8; mol wt 295.29.
C 44.74%, H 7.17%, N 4.74%, O 43.35%.
[HOCH2CH2N+(CH3)3][C6H7O7-].

Description and references

Prepn: Klein et al., US 2870198 (1959).

Properties

Granules, mp 105-107.5°. Acrid taste. Freely sol in water; very slightly sol in alcohol. Practically insol in benzene, chloroform, ether. The pH of a 25% aq soln is 4.25. May be formulated with calcium citrate for better taste and easier tabletting.

Therapeutic Category

Lipotropic.

Therapeutic Category (Veterinary)

Dietary source of choline (lipotropic factor) in poultry.

Keywords

Lipotropic