2210. Choline Theophyllinate

Nomenclature

CAS number: 4499-40-5
2-Hydroxy-N,N,N-trimethylethanaminium salt with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; theophylline cholinate; theophylline salt of choline; oxtriphylline; oxytrimethylline; Sabidal (Zyma); Teokolin; Teofilcolina; Filoral; Cholinophylline; Choledyl (Warner-Chilcott); Theoxylline; Soliphylline.
C12H21N5O3; mol wt 283.33.
C 50.87%, H 7.47%, N 24.72%, O 16.94%.

Description and references

Prepn: Ladenburg et al., US 2776287 (1957 to Nepera Chem.).

Chemical structure

Properties

White granules (contains about 60% of anhydr theophylline). One gram dissolves in 1 ml water.

Note

Also sold as Cholinophylline Magnesium Glycinate which contains 43% of anhydr theophylline.

Therapeutic Category

Bronchodilator.

Keywords

Bronchodilator; Xanthine Derivatives