2278. Cimaterol
Nomenclature
CAS number: 54239-37-1
2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile; (±)-5-[1-hydroxy-2-(isopropylamino)ethyl]anthranilonitrile; 1-(4-amino-3-cyanophenyl)-2-isopropylaminoethanol; AB-A-663; CL-263780; AC-263780. C12H17N3O; mol wt 219.28.
C 65.73%, H 7.81%, N 19.16%, O 7.30%.
Description and references
β-Adrenergic agonist, related to clenbuterol and mabuterol, q.q.v. Prepn: G. Engelhardt et al., DE 2261914 (1974 to Thomae). Pharmacology: G. Engelhardt, Arzneim.-Forsch. 34, 1625 (1984). Pharmacokinetics: T. M. Byrem et al., J. Anim. Sci. 70, 3812 (1992). Effect on lipid metabolism in sheep: C. Y. Hu et al., ibid. 66, 1393 (1988). Efficacy as a repartitioning agent in livestock: R. W. Jones et al., ibid. 61, 905 (1985); D. H. Beermann et al., ibid. 62, 370 (1986); A. P. Molony et al., Livestock Prod. Sci. 42, 23, 35 (1995).
