2343. Clazuril

Nomenclature

CAS number: 101831-36-1
2-Chloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrile; (±)-[2-chloro-4-(4,5-dihydro-3,5-dioxo-as-triazin-2(3H)-yl)phenyl](p-chlorophenyl)acetonitrile; Appertex (Janssen).
C17H10Cl2N4O2; mol wt 373.19.
C 54.71%, H 2.70%, Cl 19.00%, N 15.01%, O 8.57%.

Description and references

Prepn: G. M. Boeckx et al., EP 170316; eidem, US 4631278 (both 1986 to Janssen). Anticoccidial effect in pigeons: W. Coussement et al., Res. Vet. Sci. 45, 117 (1988).

Chemical structure

Properties

mp 196.8°.

Therapeutic Category (Veterinary)

Coccidiostat.