2408. Clorprenaline

Nomenclature

CAS number: 3811-25-4
2-Chloro-α-[[(1-methylethyl)amino]methyl]benzenemethanol; o-chloro-α-(isopropylaminomethyl)benzyl alcohol; 1-(o-chlorophenyl)-2-isopropylaminoethanol; N-(β-o-chlorophenyl-β-hydroxyethyl)isopropylamine; isoprophenamine; isoprofenamine.
C11H16ClNO; mol wt 213.70.
C 61.82%, H 7.55%, Cl 16.59%, N 6.55%, O 7.49%.

Description and references

β-Adrenergic agonist. Prepn: Mills, US 2816059 (1957 to Lilly); Nash, US 2887509 (1959 to Lilly).

Chemical structure

Derivative

Hydrochloride monohydrate.

Nomenclature

CAS number: 5588-22-7
Broncon (Wakamoto); Clopinerin (Nippon Shoji); Conselt (Sana); Fusca (Hoei); Kalutein (Tatsumi); Pentadoll (Showa Shinyaku); Restanolon (Isei).
C11H16ClNO.HCl.H2O; mol wt 268.18.
C 49.26%, H 7.14%, Cl 26.44%, N 5.22%, O 11.93%.

Properties

mp 163-164°.

Therapeutic Category

Bronchodilator.

Keywords

β-Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives