2415. Clothiapine

Nomenclature

CAS number: 2058-52-8
2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]thiazepine; Entumine (Wander); Etumine (Wander).
C18H18ClN3S; mol wt 343.87.
C 62.87%, H 5.28%, Cl 10.31%, N 12.22%, S 9.32%.

Description and references

Prepn: FR CAM 51 (1964 to Dr. A. Wander), C.A. 61, 8328h (1964).

Chemical structure

Properties

Crystals from ether + petr ether, mp 118-120°.

Therapeutic Category

Antipsychotic.

Keywords

Antipsychotic; Other Tricyclics