2421. Cloxotestosterone

Nomenclature

CAS number: 53608-96-1
(17β)-17-(2,2,2-Trichloro-1-hydroxyethoxy)androst-4-en-3-one; testosterone 17-chloral hemiacetal.
C21H29Cl3O3; mol wt 435.81.
C 57.87%, H 6.71%, Cl 24.40%, O 11.01%.

Description and references

Prepn: P. Borrevang, US 2933514 (1960 to L"ovens Kemiske Fabrik); idem, Acta Chem. Scand. 16, 883 (1962).

Chemical structure

Properties

Crystals from ethyl acetate, mp 200-201°. uv max (ethanol): 241 nm (ε 16300).

Derivative

Acetate.

Nomenclature

CAS number: 13867-82-8
Caprosem (A. B. Leo).
C23H31Cl3O4; mol wt 477.85.
C 57.81%, H 6.54%, Cl 22.26%, O 13.39%.

Properties

Crystals from ethyl acetate, mp 192-193°. uv max (ethanol): 241 nm (ε 16400).

Therapeutic Category

Androgen.

Keywords

Androgen