2489. Colpormon

Nomenclature

CAS number: 1247-71-8
(16α)-3,16-Bis(acetyloxy)estra-1,3,5(10)-trien-17-one; 3,16α-dihydroxyestra-1,3,5(10)-trien-17-one diacetate; 16α-hydroxyestrone diacetate; 3,16α-diacetoxy-Δ1,3,5-estratrien-17-one; Colpogynon.
C22H26O5; mol wt 370.44.
C 71.33%, H 7.07%, O 21.60%.

Description and references

Prepn: Leeds et al., J. Am. Chem. Soc. 76, 2943 (1954); FR M1390 (1962 to Lab. Albert Rolland), C.A. 58, 3484c (1963).

Chemical structure

Properties

Crystals, mp 179-180°. [α]D28 +122° (chloroform).

Therapeutic Category

Estrogen.

Keywords

Estrogen; Steroidal