2518. Coparaffinate

Nomenclature

CAS number: 8001-60-3
Isopar.

Description and references

A mixture of water-insol isoparaffinic acids partially neutralized with hydroxybenzyldialiphatic amines. The water-insol isoparaffinic acids are obtained by oxidation of petroleum hydrocarbons by the passage of a current of oxygen under pressure at an elevated temp in the presence of a metal catalyst. The water-insol mono- and dicarboxylic acids with from 6 to 16 carbon atoms are separated and purified by fractional distillation. The hydroxybenzyldialiphatic amines are combined directly with the isoparaffinic acids or in suitable solvent. The latter is then removed by distillation: C. E. Earle, US 2262720 (1941).

Properties

Dark-brown, viscous, oily liq. Odor of burnt petroleum. d 0.970-0.980. Immiscible with water. Freely sol in alc, volatile and fixed oils. Marketed as a 17% ointment, which also contains 4% titanium dioxide in an ointment base consisting of beeswax, cetyl alcohol, lanolin, and petrolatum.

Therapeutic Category

Antifungal (topical).

Keywords

Antifungal (Synthetic)