2583. m-Cresyl Acetate

Nomenclature

CAS number: 122-46-3
Acetic acid 3-methylphenyl ester; m-tolyl acetate; m-cresol acetic acid ester; acetic acid m-cresol ester; acetylmetacresol; metacresol acetate; Cresatin.
C9H10O2; mol wt 150.17.
C 71.98%, H 6.71%, O 21.31%.

Description and references

Germicide with pain-relieving properties. Prepn: Claus, Hirsch, J. Prakt. Chem. [2] 39, 62 (1889); Eijkman, Chem. Weekbl. 1, 453 (1904); see also US 1031971 (1912 to N. Sulzberger). Purification: Lebeau-Janot, Traité Pharm. Chim. II, 882 (Paris, 1955). Use in dentistry: J. M. Gergely, P. M. DiFiore, Gen. Dent. 41, 328 (1993).

Chemical structure

Properties

Oily liquid. Volatile with steam. Characteristic phenolic odor with a reminiscence of acetone. d426 1.048. bp 212°; bp13 99°. uv max (methanol): 262.5, 269.5 nm. Practically insol in water, glycerol. Miscible with alc, ether, chloroform, petr ether, benzene. Soly in liquid petrolatum about 5%. Also sol in cottonseed oil.

Therapeutic Category

Antiseptic (topical).

Therapeutic Category (Veterinary)

Antiseptic (topical).

Keywords

Antiseptic/Disinfectant