2681. Cyadox

Nomenclature

CAS number: 65884-46-0
[(1,4-Dioxido-2-quinoxalinyl)methylene]hydrazide cyanoacetic acid; 2-formylquinoxaline-1,4-dioxide cyanoacetylhydrazone.
C12H9N5O3; mol wt 271.23.
C 53.14%, H 3.34%, N 25.82%, O 17.70%.

Description and references

Antimicrobial growth promoting feed additive for poultry, calves and pigs. Growth promoting effects in chickens: J. Broz, B. Sevcik, Biol. Chem. Vyz. Zvirat 13, 357, 375 (1977). Prepn: J. Hebky et al., DE 2829580; eidem, US 4225604 (1979, 1980 both to Spofa). Adsorptive voltammetry determn in plasma: I. Sestáková, M. Kopanica, Talanta 35, 816 (1988). LC determn in animal feeds and gastrointestinal samples: G. J. De Graaf, T. J. Spierenburg, J. Chromatogr. 447, 244 (1988); in goat tissue: Y. Zhang et al., Anal. Sci. 21, 1495 (2005). Heat stability study: idem et al., J. Agric. Food Chem. 53, 9737 (2005). Subchronic toxicity study: G. Fang et al., Food Chem. Toxicol. 44, 36 (2006).

Chemical structure

Properties

Yellow solid, mp 255-260°. Light sensitive.

Therapeutic Category (Veterinary)

Growth promotant.