Has been isolated from human hair oxidized with permanganate: Lissizin, Z. Physiol. Chem. 173, 309 (1928). Occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather: Martin, Synge, Adv. Protein Chem. 2, 3 (1945). Prepd from cystine or cysteine by oxidation with bromine in water: Friedmann, Beitr. Chem. Physiol. Pathol. 3, 25, 38; Gortner, Hoffman, J. Biol. Chem. 72, 435 (1927).