2973. Diallyl Trisulfide
Nomenclature
CAS number: 2050-87-5
Di-2-propen-1-yl trisulfide; allyl trisulfide; DATS. C6H10S3; mol wt 178.34.
C 40.41%, H 5.65%, S 53.94%.
Description and references
Component of the essential oil of garlic; formed by pyrolysis of diallyl disulfide. Major component of the Chinese traditional medicine, allitridium. Exhibits antifungal, antitumor and antioxidant activity. Isoln from garlic oil: F. W. Semmler, Arch. Pharm. 230, 434 (1892); E. Block et al., J. Am. Chem. Soc. 110, 7813 (1988). Synthesis: B. Milligan et al., J. Chem. Soc. 1961, 4850; A. Banerji, G. P. Kalena, Tetrahedron Lett. 21, 3003 (1980). Inhibitory effect on mammary tumor cells in vitro: S. G. Sundaram, J. A. Milner, Cancer Lett. 74, 85 (1993). Mechanism of action study: X. Hu et al., Arch. Biochem. Biophys. 336, 199 (1996). Antifungal activity: J. Shen et al., Planta Med. 62, 415 (1996).
