2988. Diampromide

Nomenclature

CAS number: 552-25-0
N-[2-[Methyl(2-phenylethyl)amino]propyl]-N-phenylpropanamide; N-[2-(methylphenethylamino)propyl]propionanilide.
C21H28N2O; mol wt 324.46.
C 77.74%, H 8.70%, N 8.63%, O 4.93%.

Description and references

Opioid analgesic. Synthesis: Wright et al., J. Am. Chem. Soc. 81, 1518 (1959); US 2944081 (1960 to American Cyanamid).

Chemical structure

Properties

Liquid, bp0.5 174-178°. nD26 1.546.

Derivative

Sulfate.
C21H30N2O5S; mol wt 422.54.
C 59.69%, H 7.16%, N 6.63%, O 18.93%, S 7.59%.

Properties

Crystals from ethanol + ether, mp 110-111°.

Note

This is a controlled substance (opiate): 21 CFR, 1308.11.