3126. N,N-Diethylphenylacetamide
Nomenclature
Description and references
Substituted amide with broad spectrum repellent activity. Prepn: G. Hausknecht, Ber. 22, 324 (1889); R. Mukherjee, J. Chem. Soc. D 1971, 1113; and structure-activity relationship studies: M. V. S. Suryanarayana et al., J. Pharm. Sci. 80, 1055 (1991). Comparative studies with deet and dimethyl phthalate, q.q.v., vs mosquitoes, black flies and land leeches: S. Kumar et al., Indian J. Med. Res. 80, 541 (1984); vs bedbugs: idem et al., ibid. 102, 20 (1995); vs rat flea: K. K. Mathur et al., ibid. 83, 466 (1986); vs sandflies: M. Kalyanasundaram et al., Med. Vet. Entomol. 8, 68 (1994). Comparison with deet and dibutyl phthalate, q.q.v., in prevention of scrub typhus: R. Tilak et al., Indian J. Med. Res. 113, 98 (2001). GC determn in urine: S. S. Rao et al., J. Chromatogr. B 493, 210 (1989). Toxicity and metabolism studies: idem. et al., Toxicology 58, 81 (1989); idem et al., Toxicol. Lett. 45, 67 (1989). Development of polysiloxane based slow release formulations and efficacy vs mosquitoes : D. C. Gupta et al., J. Polym. Mater. 17, 215 (2000). Review: S. S. Rao, K. M. Rao, J. Med. Entomol. 28, 303-306 (1991).
