3183. Dihydroxyaluminum Aminoacetate

Nomenclature

CAS number: 13682-92-3
(Glycinato-N,O)dihydroxyaluminum; dihydroxy(glycinato)aluminum; aluminum aminoacetate (basic); aluminum dihydroxyaminoacetate; aluminum glycinate; glycine, aluminum salt; Ada; Alamine; Alubasine; Alzinox (Berlex); Aspogen (Eaton); Dimothyn (Flint); Doraxamin (Dorsey); Elcosal; Robalate (Robins).
C2H6AlNO4; mol wt 135.05.
C 17.79%, H 4.48%, Al 19.98%, N 10.37%, O 47.39%.
NH2CH2COOAl(OH)2.

Description and references

Prepd by adding a soln of aluminum isopropoxide in isopropanol to an aq soln of glycine: Krantz et al., J. Pharmacol. 82, 247 (1944).

Properties

Very fine powder. Bland taste. Insol in water. Mixes easily with water forming suspensions which do not separate readily. At 25° the pH of the aq suspension (1 in 25) is 7.4. One gram consumes 200 ml of 0.1N HCl under conditions of the pharmacopoeial test for aluminum hydroxide gel.

Therapeutic Category

Antacid.

Keywords

Antacid