Naturally occurring alcohol; active principal of Pygeum africanum extract, q.v., that has been used to treat benign prostatic hypertrophy (BPH). Prepn: R. Willst"atter, E. W. Mayer, Ber. 41, 1475 (1908); P. A. Levene, F. A. Taylor, J. Biol. Chem. 59, 905 (1924). Surface thermodynamic properties: S. Pathak, S. S. Katti, J. Chem. Eng. Data 14, 359 (1969). GC-MS determn in Pygeum africanum extract: N. Pierini et al., Boll. Chim. Farm. 121, 27 (1982). Antiviral activity: D. H Katz et al., Ann. N.Y. Acad. Sci. 724, 472 (1994). Study of mechanism of action in BPH: J. Müntzing et al., Invest. Urol. 17, 176 (1979); vs herpes simplex virus: L. E. Pope et al., Antiviral Res. 40, 85 (1998). Clinical evaluation in recurrent herpes labialis: L. Habbema et al., Acta Derm. Venereol. 76, 479 (1996).
Antiviral (topical).
Antiviral