3473. Dyclonine

Nomenclature

CAS number: 586-60-7
1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone; 3-piperidino-4′-butoxypropiophenone; β-piperidinoethyl-4-butoxyphenyl ketone; 4-butoxy-β-piperidinopropiophenone; 4-n-butoxy-β-(1-piperidyl)propiophenone; 4-butoxyphenyl piperidineethyl ketone; 2-(1-piperidyl)ethyl p-butoxyphenyl ketone.
C18H27NO2; mol wt 289.41.
C 74.70%, H 9.40%, N 4.84%, O 11.06%.

Description and references

Prepd from p-butoxyacetophenone by condensation with formaldehyde and piperidine hydrochloride: Pofft, Chem. Tech. (Berlin) 4, 241 (1952), C.A. 47, 10531 (1953).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 536-43-6
Dyclone (Dow); Tanaclone (Amsa).
C18H27NO2.HCl; mol wt 325.87.
C 66.34%, H 8.66%, N 4.30%, O 9.82%, Cl 10.88%.

Properties

Crystals, mp 175-176°. Sol in water, alc, acetone. Phenol coefficient 3.6.

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)