3583. Enilconazole

Nomenclature

CAS number: 35554-44-0
1-[2-(2,4-Dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole; (±)-1-[β-(allyloxy)-2,4-dichlorophenethyl]imidazole; imazalil; R-23979; Clinafarm (Janssen); Imaverol (Janssen).
C14H14Cl2N2O; mol wt 297.18.
C 56.58%, H 4.75%, Cl 23.86%, N 9.43%, O 5.38%.

Description and references

Broad spectrum antimycotic with agricultural and veterinary applications. Prepn: E. F. Godefroi, J. L. Schuermans, DE 2063857; eidem, US 3658813 (1971, 1972 both to Janssen). Efficacy vs citrus decay: P. R. Harding, Plant Dis. Rep. 60, 643 (1976); S. Ben-Yehoshua et al., Pestic. Sci. 12, 485 (1981). Biological and toxicological properties: D. Thienpont et al., Arzneim.-Forsch. 31, 309 (1981). Residue analysis in treated grapefruit: E. R. Stein et al., J. Environ. Sci. Health B16, 427 (1981).

Chemical structure

Properties

Solidified oil. Slightly sol in organic solvents; poorly sol in water.

Use

As a disinfectant for stable and kennel equipment; exptly as an agricultural fungicide.

Therapeutic Category

Antifungal.

Therapeutic Category (Veterinary)

Antifungal.

Keywords

Antifungal (Synthetic); Imidazoles