3677. Erythrityl Tetranitrate

Nomenclature

CAS number: 7297-25-8
(2R,3S)-rel-1,2,3,4-Butanetetroltetranitrate; erythritol tetranitrate; erythrol tetranitrate; tetranitrol; tetranitrin; nitroerythrite; Cardilate (Burroughs Wellcome); Cardiloid.
C4H6N4O12; mol wt 302.11.
C 15.90%, H 2.00%, N 18.55%, O 63.55%.

Description and references

Made by nitration of erythritol.

Properties

Leaflets from alcohol, mp 61°. Sol in alcohol, ether, glycerol. Insol in water. Reduces Fehling's soln. Explodes on percussion. Its use in pharmaceutical preparations is only in admixture with carbohydrate substances such as lactose. Sold in tablet form only. Such tablets are nonexplosive.

Therapeutic Category

Vasodilator (coronary).

Therapeutic Category (Veterinary)

Vasodilator.

Keywords

Vasodilator (Coronary)